Metastatic carcinoma of unknown primary (CUP) has a very poor prognosis, and no standard first-line therapy currently exists.Here, we report the results of a phase II study utilizing a combination of gemcitabine and irinotecan as first-line therapy.Treatment was with gemcitabine 1000 mg/m(2) and irinotecan 75 mg/m(2) weekly times four on a six week

Biomimetics must be taught to the next generation of designers in the interest of delivering solutions for current problems.Teaching biomimetics involves teachers and students from and in various disciplines at different stages of the educational system.There is no common understanding of how and what to teach in the different phases of the educati

Under the alternating load, the chain of high-speed heavy-duty bucket hoist passes through hundreds of thousands or more shocks, NECK STRIPS and the final failure mode is mainly chain plate fatigue fracture.There is no report on this kind of chain fatigue tester at home and abroad.Through force analysis of chain plate, theoretical basis is provided

The article focuses on the scientific and practical aspects of establishing a comprehensive system of environmental compliance for industrial and household waste landfills, Laser including the system of industrial and environmental monitoring and control, modern innovations in the field of instrumental-analytical control of the state of environment